Olopatadine/mometasone
| Combination of | |
|---|---|
| Olopatadine | Selective histamine H1-receptor antagonist |
| Mometasone | Corticosteroid |
| Clinical data | |
| Trade names | Ryaltris |
| Other names | GSP 301 |
| License data | |
| Pregnancy category |
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| Routes of administration | Nasal spray |
| ATC code |
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| Legal status | |
| Legal status | |
| Identifiers | |
| KEGG | |
Olopatadine/mometasone, sold under the brand name Ryaltris, is a fixed-dose combination medication for the treatment of allergic rhinitis and rhinoconjunctivitis in adults and adolescents twelve years of age and older.[1][2][3] It contains olopatadine hydrochloride and mometasone furoate monohydrate.[1][2] It is sprayed into the nose.[1][2]
Common side effects include an unpleasant taste (dysgeusia).[1]
It was approved for medical use in Australia in December 2019,[1][4] and in the United States in January 2022.[2]
References[edit]
- ^ a b c d e f g "Ryaltris (olopatadine hydrochloride and mometasone furoate monohydrate) Nasal Spray". Retrieved 25 July 2020.
- ^ a b c d e "Ryaltris- olopatadine hydrochloride and mometasone furoate spray, metered". DailyMed. 9 January 2022. Retrieved 20 June 2022.
- ^ Chen R, Zheng D, Zhang Y, Sima G (September 2021). "Efficacy and safety of twice-daily olopatadine-mometasone combination nasal spray (GSP301) in the treatment of allergic rhinitis: a systematic review and meta-analysis". European Archives of Oto-rhino-laryngology. 279 (4): 1691–1699. doi:10.1007/s00405-021-07085-w. PMID 34591150. S2CID 238223252.
- ^ "Ryaltris nasal spray approved in Australia". OINDPnews. 20 December 2019. Retrieved 25 July 2020.
External links[edit]
- "Olopatadine". Drug Information Portal. U.S. National Library of Medicine.
- "Mometasone furoate". Drug Information Portal. U.S. National Library of Medicine.
- Clinical trial number NCT02631551 for "Efficacy and Safety of Fixed Dose Combination GSP 301 Nasal Spray (NS) in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301-301)" at ClinicalTrials.gov
- Clinical trial number NCT02870205 for "Efficacy and Safety of GSP 301 Nasal Spray in the Treatment of Seasonal Allergic Rhinitis (SAR) (GSP 301-304)" at ClinicalTrials.gov
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